The Glycerin GTS is Brooks’s most cushioned stability shoe, and the Glycerin GTS 22 features in our best running shoes for flat feet guide. Low arches often start an excessive inward roll at heel strike. The Glycerin GTS counters that with a wide heel base and holistic GuideRails that only apply corrective force when the foot drifts out of its natural motion corridor.
Its dual-cell DNA Tuned foam uses larger cells in the heel for pillowy shock absorption and smaller, denser cells in the forefoot for stable push-offs. The result is high-cushion comfort with a firm baseline. Energy return is modest, though, and the thick upper runs warm in hot weather.
The Glycerin GTS 23 replaced the GTS 22 in early 2026, adding a little more foam and lowering the drop. The specs here are from the GTS 22 we reviewed.
Who it’s for: runners with flat feet and moderate overpronation who want maximum cushioning.

